Assay
Age
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Immunohistochemistry (whole mount)
10.5 DPC
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Runx1 runt related transcription factor 1 (Synonyms: AML1, Cbfa2, Pebp2a2, runt domain, alpha subunit 2) | |
Results | Reference |
1 | J:323133 Bennett LF, Mumau MD, Li Y, Speck NA, MyD88-dependent TLR signaling oppositely regulates hematopoietic progenitor and stem cell formation in the embryo. Development. 2022 Apr 15;149(8):dev200025 |
1 | J:345606 Gonzalez Galofre ZN, Kilpatrick AM, Marques M, Sa da Bandeira D, Ventura T, Gomez Salazar M, Bouilleau L, Marc Y, Barbosa AB, Rossi F, Beltran M, van de Werken HJG, van IJcken WFJ, Henderson NC, Forbes SJ, Crisan M, Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun. 2024 Feb 23;15(1):1653 |
1 | J:247822 Jiang X, Hawkins JS, Lee J, Lizama CO, Bos FL, Zape JP, Ghatpande P, Peng Y, Louie J, Lagna G, Zovein AC, Hata A, Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice. Nat Commun. 2017 Jul 25;8(1):128 |
1 | J:214903 Kataoka H, Hayashi M, Kobayashi K, Ding G, Tanaka Y, Nishikawa S, Region-specific Etv2 ablation revealed the critical origin of hemogenic capacity from Hox6-positive caudal-lateral primitive mesoderm. Exp Hematol. 2013 Jun;41(6):567-581.e9 |
1 | J:325982 Klaus A, Clapes T, Yvernogeau L, Basu S, Weijts B, Maas J, Smal I, Galjart N, Robin C, CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development. Cell Rep. 2022 Jun 14;39(11):110957 |
1 | J:342845 Munera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AA, Chatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu YC, Takebe T, Helmrath MA, Wells JM, Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon. Cell Stem Cell. 2023 Nov 2;30(11):1434-1451.e9 |
1 | J:264757 Neo WH, Booth CAG, Azzoni E, Chi L, Delgado-Olguin P, de Bruijn MFTR, Jacobsen SEW, Mead AJ, Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells. Blood. 2018 May 17;131(20):2223-2234 |
1 | J:316414 Neo WH, Meng Y, Rodriguez-Meira A, Fadlullah MZH, Booth CAG, Azzoni E, Thongjuea S, de Bruijn MFTR, Jacobsen SEW, Mead AJ, Lacaud G, Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors. Nat Commun. 2021 Dec 2;12(1):7019 |
1 | J:264119 Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M, A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018 May 17;145(10):dev160184 |
1 | J:339095 Silverio-Alves R, Kurochkin I, Rydstrom A, Vazquez Echegaray C, Haider J, Nicholls M, Rode C, Thelaus L, Lindgren AY, Ferreira AG, Brandao R, Larsson J, de Bruijn MFTR, Martin-Gonzalez J, Pereira CF, GATA2 mitotic bookmarking is required for definitive haematopoiesis. Nat Commun. 2023 Aug 14;14(1):4645 |
1 | J:304773 Yvernogeau L, Klaus A, Maas J, Morin-Poulard I, Weijts B, Schulte-Merker S, Berezikov E, Junker JP, Robin C, Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta. Blood. 2020 Aug 13;136(7):831-844 |
1* | J:235365 Yzaguirre AD, Speck NA, Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites. Dev Dyn. 2016 Oct;245(10):1011-28 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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